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METTL7B Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q6UX53 |
| Other Accession | Q562C4, Q9DD20, NP_689850.2 |
| Reactivity | Human, Mouse |
| Predicted | Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 27775 Da |
| Antigen Region | 37-63 aa |
| Gene ID | 196410 |
|---|---|
| Other Names | Methyltransferase-like protein 7B, 211-, METTL7B |
| Target/Specificity | This METTL7B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-63 amino acids from the N-terminal region of human METTL7B. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | METTL7B Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TMT1B {ECO:0000303|PubMed:37137720, ECO:0000312|HGNC:HGNC:28276} |
|---|---|
| Function | Thiol S-methyltransferase that catalyzes the transfer of a methyl group from S-adenosyl-L-methionine to alkyl and phenolic thiol- containing acceptor substrates. Together with TMT1B accounts for most of S-thiol methylation activity in the endoplasmic reticulum of hepatocytes. Selectively methylates S-centered nucleophiles from metabolites such as hydrogen sulfide and dithiothreitol. |
| Cellular Location | Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q562C4}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q562C4}. Lipid droplet {ECO:0000250|UniProtKB:Q562C4}. Microsome. Cytoplasm, cytosol. Note=Highly concentrated in the perinuclear area of the endoplasmic reticulum (ER) and surrounding lipid droplets. May be associated with the specific regions of the LR that form lipid droplets and targeted to the initial deposits of lipids where the lipid droplets form. {ECO:0000250|UniProtKB:Q562C4} |
| Tissue Location | Expressed in the liver. |
Research Areas
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
Background
METTL7B is probable methyltransferase (By similarity).
References
Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
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$ 182.50
$ 70.00
Cat# AP18067a
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