|Application ||WB, E|
|Other Accession||Q8R555, NP_060528.3|
|Calculated MW||71421 Da|
|Antigen Region||130-156 aa|
|Other Names||Cartilage acidic protein 1, 68 kDa chondrocyte-expressed protein, CEP-68, ASPIC, CRTAC1, ASPIC1, CEP68|
|Target/Specificity||This CRTAC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 130-156 amino acids from the N-terminal region of human CRTAC1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CRTAC1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Cellular Location||Secreted, extracellular space, extracellular matrix|
|Tissue Location||Expressed in the interterritorial matrix of articular deep zone cartilage (at protein level). Isoform 1 and isoform 2 are expressed in brain. Isoform 1 is detected in lung and chondrocytes. Detected in cartilage, bone, cultured chondrocytes and lung, and at low levels in heart. Not detected in osteoblasts.|
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Provided below are standard protocols that you may find useful for product applications.
The function of this protein remains unknown.
Sebastiani, P., et al. Science (2010) In press :
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Zabaneh, D., et al. PLoS ONE 5 (8), E11961 (2010) :
Grgurevic, L., et al. Int Orthop 31(6):743-751(2007)
Steck, E., et al. Matrix Biol. 26(1):30-41(2007)
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