|Application ||WB, E|
|Other Accession||Q4R568, NP_005909.2|
|Calculated MW||35503 Da|
|Antigen Region||297-326 aa|
|Other Names||Malate dehydrogenase, mitochondrial, MDH2|
|Target/Specificity||This MDH2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 297-326 amino acids from the C-terminal region of human MDH2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||MDH2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Cellular Location||Mitochondrion matrix.|
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Provided below are standard protocols that you may find useful for product applications.
Malate dehydrogenase catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. The protein encoded by this gene is localized to the mitochondria and may play pivotal roles in the malate-aspartate shuttle that operates in the metabolic coordination between cytosol and mitochondria. [provided by RefSeq].
Rose, J. Phd, et al. Mol. Med. (2010) In press :
Rzem, R., et al. J. Inherit. Metab. Dis. 30(5):681-689(2007)
Luo, C., et al. J. Biochem. Biophys. Methods 68(2):101-111(2006)
Kullberg, M., et al. Mol. Biol. Evol. 23(8):1493-1503(2006)
Andersen, J.S., et al. Nature 433(7021):77-83(2005)
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