TSPAN18 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | Q96SJ8 |
Other Accession | NP_570139.3 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 27710 Da |
Antigen Region | 93-120 aa |
Gene ID | 90139 |
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Other Names | Tetraspanin-18, Tspan-18, TSPAN18 |
Target/Specificity | This TSPAN18 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 93-120 amino acids from the Central region of human TSPAN18. |
Dilution | WB~~1:2000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | TSPAN18 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | TSPAN18 (HGNC:20660) |
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Function | Plays a role in the cell surface localization of ORAI1 and may participate in the regulation of Ca(2+) signaling and the VWF release in response to inflammatory stimuli. |
Cellular Location | Membrane; Multi-pass membrane protein |
Tissue Location | Highly expressed in primary endothelial cells (PubMed:30573509, PubMed:32694189). Expressed in the embryo heart (PubMed:32694189). Weakly expressed the embryo skeletal muscle (PubMed:32694189). |
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Provided below are standard protocols that you may find useful for product applications.
Background
The function of this protein remains unknown.
References
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Hemler, M.E. J. Cell Biol. 155(7):1103-1107(2001)
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