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AFF2 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - AFF2 Antibody (Center) AP18150c
    AFF2 Antibody (Center) (Cat. #AP18150c) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the AFF2 antibody detected the AFF2 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P51816
Other Accession NP_001162593.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 144771 Da
Antigen Region 886-912 aa
Additional Information
Gene ID 2334
Other Names AF4/FMR2 family member 2, Fragile X E mental retardation syndrome protein, Fragile X mental retardation 2 protein, FMR2P, Protein FMR-2, Protein Ox19, AFF2, FMR2, OX19
Target/Specificity This AFF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 886-912 amino acids from the Central region of human AFF2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsAFF2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name AFF2
Synonyms FMR2, OX19
Function RNA-binding protein. Might be involved in alternative splicing regulation through an interaction with G-quartet RNA structure.
Cellular Location Nucleus speckle. Note=When splicing is inhibited, accumulates in enlarged speckles
Tissue Location Brain (most abundant in hippocampus and amygdala), placenta and lung
Research Areas
Citations (0)

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This gene encodes a putative transcriptional activator that is a member of the AF4FMR2 gene family. This gene is associated with the folate-sensitive fragile X E locus on chromosome X. A repeat polymorphism in the fragile X E locus results in silencing of this gene causing Fragile X E syndrome. Fragile X E syndrome is a form of nonsyndromic X-linked mental retardation. Alternate splicing results in multiple transcript variants.


Bensaid, M., et al. Nucleic Acids Res. 37(4):1269-1279(2009)
Brylawski, B.P., et al. Exp. Mol. Pathol. 82(2):190-196(2007)
Sharma, D., et al. Genet. Epidemiol. 20(1):129-144(2001)
Hillman, M.A., et al. J. Hum. Genet. 46(5):251-259(2001)
Musumeci, S.A., et al. Clin Neurophysiol 111(9):1632-1636(2000)

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$ 295.00
$ 99.00
Cat# AP18150c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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