|Application ||WB, E|
|Calculated MW||32580 Da|
|Antigen Region||78-107 aa|
|Other Names||Mitochondrial ornithine transporter 2, Solute carrier family 25 member 2, SLC25A2, ORNT2|
|Target/Specificity||This ORNT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 78-107 amino acids from the Central region of human ORNT2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ORNT2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Ornithine transport across inner mitochondrial membrane, from the cytoplasm to the matrix.|
|Cellular Location||Mitochondrion inner membrane; Multi-pass membrane protein|
|Tissue Location||Expressed in liver, kidney, pancreas and cultured fibroblasts|
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Provided below are standard protocols that you may find useful for product applications.
Located between the protocadherin beta and gamma gene clusters on chromosome 5, this intronless gene encodes a protein that is highly similar to an ornithine transporter localized in the mitochondrial inner membrane. The encoded protein most likely plays a role in metabolism as a mitochondrial transport protein.
Trynka, G., et al. Gut 58(8):1078-1083(2009)
Fiermonte, G., et al. J. Biol. Chem. 278(35):32778-32783(2003)
Camacho, J.A., et al. Mol. Genet. Metab. 79(4):257-271(2003)
Wu, Q., et al. Genome Res. 11(3):389-404(2001)
Porter, R.K. Biochim. Biophys. Acta 1459 (2-3), 356-362 (2000) :
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