|Application ||WB, E|
|Other Accession||Q4R6Q7, NP_060699.3|
|Calculated MW||54767 Da|
|Antigen Region||356-384 aa|
|Other Names||AP-5 complex subunit mu-1, Adaptor-related protein complex 5 subunit mu-1, Mu5, Mu-2-related death-inducing protein, MuD, Putative HIV-1 infection-related protein, AP5M1, C14orf108, MUDENG|
|Target/Specificity||This MUDEN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 356-384 amino acids from the C-terminal region of human MUDEN.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||MUDEN Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||As part of AP-5, a probable fifth adaptor protein complex it may be involved in endosomal transport. According to PubMed:18395520, it may play a role in cell death.|
|Cellular Location||Cytoplasm, cytosol. Late endosome membrane; Peripheral membrane protein; Cytoplasmic side. Lysosome membrane; Peripheral membrane protein; Cytoplasmic side. Note=May cycle on and off membranes|
|Tissue Location||Expressed in various tumor cell lines including Jurkat, Hep-G2 and HeLa.|
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Provided below are standard protocols that you may find useful for product applications.
MUDENG may play an important role in cell death.
Lee, M.R., et al. Biochem. Biophys. Res. Commun. 370(3):504-508(2008)
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