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ENPP4 Antibody (Center)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - ENPP4 Antibody (Center) AP18179c
    ENPP4 Antibody (Center) (Cat. #AP18179c) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the ENPP4 antibody detected the ENPP4 protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q9Y6X5
Other Accession A2VDP5, NP_055751.1
Reactivity Human
Predicted Bovine
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 51641 Da
Antigen Region 171-200 aa
Additional Information
Gene ID 22875
Other Names Bis(5'-adenosyl)-triphosphatase ENPP4, AP3A hydrolase, AP3Aase, Ectonucleotide pyrophosphatase/phosphodiesterase family member 4, E-NPP 4, NPP-4, ENPP4, KIAA0879, NPP4
Target/Specificity This ENPP4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 171-200 amino acids from the Central region of human ENPP4.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsENPP4 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ENPP4
Synonyms KIAA0879, NPP4
Function Hydrolyzes extracellular Ap3A into AMP and ADP, and Ap4A into AMP and ATP. Ap3A and Ap4A are diadenosine polyphosphates thought to induce proliferation of vascular smooth muscle cells. Acts as a procoagulant, mediating platelet aggregation at the site of nascent thrombus via release of ADP from Ap3A and activation of ADP receptors.
Cellular Location Cell membrane; Single-pass type I membrane protein
Tissue Location Expressed on the surface of vascular endothelia.
Research Areas
Citations (0)
citation

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Background

ENPP4 belongs to the nucleotide pyrophosphatase/phosphodiesterase family.

References

Olsen, J.V., et al. Cell 127(3):635-648(2006)
Gijsbers, R., et al. J. Biol. Chem. 276(2):1361-1368(2001)

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$ 182.50
$ 70.00
Cat# AP18179c
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