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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   ENTPD4 Antibody (N-term)   

ENTPD4 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - ENTPD4 Antibody (N-term) AP18180A
    ENTPD4 Antibody (N-term) (Cat. #AP18180a) western blot analysis in mouse spleen tissue lysates (35ug/lane).This demonstrates the ENTPD4 antibody detected the ENTPD4 protein (arrow).
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q9Y227
Other Accession NP_001122402.1
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 70255 Da
Antigen Region 40-69 aa
Additional Information
Gene ID 9583
Other Names Ectonucleoside triphosphate diphosphohydrolase 4, NTPDase 4, Lysosomal apyrase-like protein of 70 kDa, Uridine-diphosphatase, UDPase, ENTPD4, KIAA0392, LALP70, LYSAL1
Target/Specificity This ENTPD4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 40-69 amino acids from the N-terminal region of human ENTPD4.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsENTPD4 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ENTPD4
Synonyms KIAA0392, LALP70, LYSAL1
Function Hydrolyzes preferentially nucleoside 5'-diphosphates, nucleoside 5'-triphosphates are hydrolyzed only to a minor extent. The order of activity with different substrates is UDP >> GDP = CDP = TDP, AMP, ADP, ATP and UMP are not substrates. Preferred substrates for isoform 2 are CTP, UDP, CDP, GTP and GDP, while isoform 1 utilizes UTP and TTP.
Cellular Location Golgi apparatus membrane; Multi-pass membrane protein. Cytoplasmic vesicle, autophagosome membrane; Multi-pass membrane protein. Note=Localizes in the Golgi and autophagic vacuoles/lysosomes
Tissue Location Ubiquitous. Highest expression in testis and lowest in bladder
Research Areas
Citations (0)

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Background

ENTPD4 hydrolyzes preferentially nucleoside 5'-diphosphates, nucleoside 5'-triphosphates are hydrolyzed only to a minor extent. The order of activity with different substrates is UDP >> GDP = CDP = TDP, AMP, ADP, ATP and UMP are not substrates. Preferred substrates for isoform 2 are CTP, UDP, CDP, GTP and GDP, while isoform 1 utilizes UTP and TTP.

References

Saito, A., et al. Psychiatry Res (2010) In press :
Joslyn, G., et al. Alcohol. Clin. Exp. Res. 34(5):800-812(2010)
Rush, J., et al. Nat. Biotechnol. 23(1):94-101(2005)
Rush, J., et al. Nat. Biotechnol. 23(1):94-101(2005)
Biederbick, A., et al. BMC Biochem. 5, 8 (2004) :

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$ 295.00
$ 99.00
Cat# AP18180A
Size:
Quantity:
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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