|Application ||WB, E|
|Calculated MW||22283 Da|
|Antigen Region||22-48 aa|
|Other Names||Membrane-spanning 4-domains subfamily A member 5, CD20 antigen-like 2, Testis-expressed transmembrane protein 4, MS4A5, CD20L2, TETM4|
|Target/Specificity||This MS4A5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 22-48 amino acids from the N-terminal region of human MS4A5.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||MS4A5 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May be involved in signal transduction as a component of a multimeric receptor complex.|
|Cellular Location||Membrane; Multi-pass membrane protein.|
|Tissue Location||Expressed at high level in the testis. Detected also in the pancreas, heart and in the brain|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. Though this member is not expressed in hematopoietic cells specifically, it may be involved in signal transduction like many of its related family members. The gene encoding this protein is localized to 11q12, among a cluster of family members.
Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Liang, Y., et al. Immunogenetics 53(5):357-368(2001)
Liang, Y., et al. Genomics 72(2):119-127(2001)
Ishibashi, K., et al. Gene 264(1):87-93(2001)
Hulett, M.D., et al. Biochem. Biophys. Res. Commun. 280(1):374-379(2001)
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