|Application ||WB, E|
|Other Accession||P0C5X8, Q9D3A9, Q9MZZ8, Q2KJ98, NP_001005367.1|
|Predicted||Bovine, Monkey, Mouse, Rat|
|Calculated MW||49051 Da|
|Antigen Region||2-28 aa|
|Other Names||Protein tweety homolog 1, hTTY1, TTYH1|
|Target/Specificity||This TTYH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 2-28 amino acids from the N-terminal region of human TTYH1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||TTYH1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Probable chloride channel. May be involved in cell adhesion (By similarity).|
|Cellular Location||Cell membrane; Multi-pass membrane protein|
|Tissue Location||Expressed in brain, eye, ovary and testis, and at lower levels in muscle, placenta, liver and lung|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the tweety family of proteins. Members of this family function as chloride anion channels. The encoded protein functions as a calcium(2+)-independent, volume-sensitive large conductance chloride(-) channel. Two transcript variants encoding distinct isoforms have been identified for this gene.
He, Y., et al. J. Biol. Chem. 283(35):24000-24010(2008)
Suzuki, M., et al. J. Biol. Chem. 279(21):22461-22468(2004)
Campbell, H.D., et al. Genomics 68(1):89-92(2000)
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