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ZFP57 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - ZFP57 Antibody (Center) AP18299C
    Anti-ZFP57 Antibody (Center) at 1:1000 dilution + human placenta lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 52 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9NU63
Other Accession NP_001103279.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 51919 Da
Antigen Region 269-296 aa
Additional Information
Gene ID 346171
Other Names Zinc finger protein 57 homolog, Zfp-57, Zinc finger protein 698, ZFP57, C6orf40, ZNF698
Target/Specificity This ZFP57 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 269-296 amino acids from the Central region of human ZFP57.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsZFP57 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ZFP57
Synonyms C6orf40, ZNF698
Function Binds to a 5'-TGCCGC-3' consensus sequence and recognizes the methylated CpG within this element (By similarity). Transcription regulator required to maintain maternal and paternal gene imprinting, a process by which gene expression is restricted in a parent of origin-specific manner by epigenetic modification of genomic DNA and chromatin, including DNA methylation. Acts by controlling DNA methylation during the earliest multicellular stages of development at multiple imprinting control regions. Required for the establishment of maternal methylation imprints at SNRPN locus. Acts as a transcriptional repressor in Schwann cells.
Cellular Location Nucleus. Note=Binds various differentially methylated regions (DMR), including the SNRPN DMR
Research Areas
Citations (0)

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The protein encoded by this gene is a zinc finger protein containing a KRAB domain. Studies in mouse suggest that this protein may function as a transcriptional repressor. Mutations in this gene have been associated with transient neonatal diabetes mellitus type 1 (TNDM1).


Spengler, S., et al. Eur J Med Genet 52(6):415-416(2009)
Barcellos, L.F., et al. PLoS Genet. 5 (10), E1000696 (2009) :
Tse, K.P., et al. Am. J. Hum. Genet. 85(2):194-203(2009)
Li, X., et al. Dev. Cell 15(4):547-557(2008)
Mackay, D.J., et al. Nat. Genet. 40(8):949-951(2008)

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$ 295.00
$ 99.00
Cat# AP18299C
(40 western blots)
Availability: In Stock
Bulk Size
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