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POU2F1 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - POU2F1 Antibody (N-term) AP18315a
    POU2F1 Antibody (N-term) (Cat. #AP18315a) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the POU2F1 Antibody detected the POU2F1 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P14859
Other Accession Q29076, P15143, NP_002688
Reactivity Human
Predicted Chicken, Pig
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 76472 Da
Antigen Region 1-30 aa
Additional Information
Gene ID 5451
Other Names POU domain, class 2, transcription factor 1, NF-A1, Octamer-binding protein 1, Oct-1, Octamer-binding transcription factor 1, OTF-1, POU2F1, OCT1, OTF1
Target/Specificity This POU2F1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human POU2F1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPOU2F1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name POU2F1
Synonyms OCT1, OTF1
Function Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR (By similarity). In case of human herpes simplex virus (HSV) infection, POU2F1 forms a multiprotein-DNA complex with the viral transactivator protein VP16 and HCFC1 thereby enabling the transcription of the viral immediate early genes.
Cellular Location Nucleus.
Tissue Location Ubiquitous. Isoform 2 is lymphocyte-specific.
Citations (0)

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The OCT1 transcription factor was among the first identified members of the POU transcription factor family (summarized by Sturm et al., 1993 [PubMed 8314572]). Members of this family contain the POU domain, a 160-amino acid region necessary for DNA binding to the octameric sequence ATGCAAAT.


Vuzman, D., et al. Biophys. J. 99(4):1202-1211(2010)
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Laurent, B., et al. Blood 115(3):687-695(2010)
Becker, M.L., et al. Pharmacogenet. Genomics 20(1):38-44(2010)

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$ 295.00
$ 99.00
Cat# AP18315a
(40 western blots)
Availability: In Stock
Bulk Size
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