CCDC147 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | Q5T655 |
Other Accession | NP_001008723.1 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 103417 Da |
Antigen Region | 16-45 aa |
Gene ID | 159686 |
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Other Names | Coiled-coil domain-containing protein 147, CCDC147, C10orf80 |
Target/Specificity | This CCDC147 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 16-45 amino acids from the N-terminal region of human CCDC147. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | CCDC147 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | CFAP58 (HGNC:26676) |
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Function | Has an essential role in the assembly and organization of the sperm flagellar axoneme (PubMed:32791035). Required for the elongation of the primary cilium and sperm flagellar midpiece via modulation of the Notch signaling pathway (By similarity). |
Cellular Location | Cell projection, cilium {ECO:0000250|UniProtKB:A8HUA1}. Cell projection, cilium, flagellum. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250|UniProtKB:B2RW38}. Note=Localized to the entire flagellum and predominantly concentrated in the midpiece. Co-localizes with ODFP2 at the centrosome (By similarity). {ECO:0000250|UniProtKB:B2RW38, ECO:0000269|PubMed:32791035} |
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Provided below are standard protocols that you may find useful for product applications.
Background
The function of this protein remains unknown.
References
Deloukas, P., et al. Nature 429(6990):375-381(2004)
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