K1712 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | Q9C0F1 |
Other Accession | NP_001035247.1 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 44140 Da |
Antigen Region | 278-307 aa |
Gene ID | 80817 |
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Other Names | Centrosomal protein of 44 kDa, Cep44, HBV PreS1-transactivated protein 3, PS1TP3, CEP44, KIAA1712 |
Target/Specificity | This K1712 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 278-307 amino acids from the C-terminal region of human K1712. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | K1712 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | CEP44 |
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Synonyms | KIAA1712 |
Function | Centriole-enriched microtubule-binding protein involved in centriole biogenesis. In collaboration with CEP295 and POC1B, is required for the centriole-to-centrosome conversion by ensuring the formation of bona fide centriole wall (PubMed:32060285). Functions as a linker component that maintains centrosome cohesion. Associates with CROCC and regulates its stability and localization to the centrosome (PubMed:31974111). |
Cellular Location | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, spindle pole. Midbody Note=Localizes to the proximal end of mother and daughter centrioles |
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Provided below are standard protocols that you may find useful for product applications.
Background
The function of this protein remains unknown.
References
Ota, T., et al. Nat. Genet. 36(1):40-45(2004)
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