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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   OSTM1 Antibody (C-term)   

OSTM1 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - OSTM1 Antibody (C-term) AP18345b
    OSTM1 Antibody (C-term) (Cat. #AP18345b) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the OSTM1 Antibody detected the OSTM1 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q86WC4
Other Accession Q8BGT0, NP_054747.2
Reactivity Human
Predicted Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 37257 Da
Antigen Region 292-321 aa
Additional Information
Gene ID 28962
Other Names Osteopetrosis-associated transmembrane protein 1, Chloride channel 7 beta subunit, OSTM1, GL
Target/Specificity This OSTM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 292-321 amino acids from the C-terminal region of human OSTM1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsOSTM1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name OSTM1
Synonyms GL
Function Required for osteoclast and melanocyte maturation and function.
Cellular Location Lysosome membrane; Single-pass type I membrane protein. Note=Requires CLCN7 to travel to lysosomes
Research Areas
Citations (0)

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This gene encodes a protein that may be involved in the degradation of G proteins via the ubiquitin-dependent proteasome pathway. The encoded protein binds to members of subfamily A of the regulator of the G-protein signaling (RGS) family through an N-terminal leucine-rich region. This protein also has a central RING finger-like domain and E3 ubiquitin ligase activity. This protein is highly conserved from flies to humans. Defects in this gene may cause the autosomal recessive, infantile malignant form of osteopetrosis.


Yerges, L.M., et al. J. Bone Miner. Res. 24(12):2039-2049(2009)
Mazzolari, E., et al. Am. J. Hematol. 84(8):473-479(2009)
Vieira, A.R., et al. Genet. Med. 10(9):668-674(2008)
Feigin, M.E., et al. Cell. Signal. 20(5):949-957(2008)
Maranda, B., et al. J. Bone Miner. Res. 23(2):296-300(2008)

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$ 295.00
$ 99.00
Cat# AP18345b
(40 western blots)
Availability: In Stock
Bulk Size
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