|Application ||WB, E|
|Calculated MW||36103 Da|
|Antigen Region||221-250 aa|
|Other Names||Neuropeptides B/W receptor type 1, G-protein coupled receptor 7, NPBWR1, GPR7|
|Target/Specificity||This NPBWR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 221-250 amino acids from the C-terminal region of human NPBWR1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||NPBWR1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Interacts specifically with a number of opioid ligands. Receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food intake and the organization of other signals. Has a higher affinity for neuropeptide B.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
|Tissue Location||Found in cerebellum and frontal cortex. Detected at high levels in hippocampus, amygdala and trachea; at moderate levels in fetal brain, pituitary gland and prostate. Not in caudate, accumbens, kidney or liver. Also detected at high levels in lung carcinoma.|
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Provided below are standard protocols that you may find useful for product applications.
NPBWR1 interacts specifically with a number of opioid ligands. Receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food intake and the organization of other signals. Has a higher affinity for neuropeptide B.
Luttrell, L.M. Mol. Biotechnol. 39(3):239-264(2008)
Lambert, N.A. Sci Signal 1 (25), RE5 (2008) :
Cottrell, S., et al. J. Urol. 177(5):1753-1758(2007)
Mazzocchi, G., et al. J. Clin. Endocrinol. Metab. 90(6):3466-3471(2005)
Zaratin, P.F., et al. Mol. Cell. Neurosci. 28(1):55-63(2005)
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