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B4GALNT1 Antibody (Center)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Country
United States
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Ordering Information
Catalog # Size Availability Price  
AP18357c 0.1 mg 400 ul In Stock $ 255.00 Add to cart
AP18357c-ev20 20 ug 100 ul In Stock $ 95.00 Add to cart
  • Specification
  • Citiations : 0
  • Reviews
  • Protocols
  • Backgrounds

B4GALNT1 Antibody (Center) - Product info

ApplicationWB
  • Applications Legend:
  • W=Western Blotting
  • IP=Immunoprecipitation
  • IHC-P=Immunohistochemistry (Paraffin)
  • IF-IC=Immunofluorescence (Immunocytochemistry)
  • F=Flow Cytometry
Primary AccessionQ00973
Other AccessionNP_001469.1
ReactivityHuman, Mouse
Concentration0.25 mg/ml
IsotypeRabbit Ig
Calculated MW58882 Da

B4GALNT1 Antibody (Center) - Additional info

Gene ID 2583
Other Names
B4GALNT1; GALGT; SIAT2; Beta-1, 4 N-acetylgalactosaminyltransferase 1; (N-acetylneuraminyl)-galactosylglucosylceramide; GM2/GD2 synthase; GalNAc-T
Target/Specificity
This B4GALNT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 295-323 amino acids from the Central region of human B4GALNT1.
Dilution
WB~~1:100~500
Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Precautions
B4GALNT1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.

B4GALNT1 Antibody (Center) - Protein Information

Name B4GALNT1
Synonyms GALGT, SIAT2
Function
Involved in the biosynthesis of gangliosides GM2, GD2 and GA2
Cellular Location
Golgi apparatus membrane; Single-pass type II membrane protein

B4GALNT1 Antibody (Center) - Related products

AP18357c: B4GALNT1 Antibody (Center)

RI10512: B4GALNT1 predesign siRNA

AT1255a: B4GALNT1 Antibody (monoclonal) (M02)

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Provided below are standard protocols that you may find useful for product applications.

BACKGROUND

GM2 and GD2 gangliosides are sialic acid-containing glycosphingolipids. GalNAc-T is the enzyme involved in the biosynthesis of G(M2) and G(D2) glycosphingolipids. GalNAc-T catalyzes the transfer of GalNAc into G(M3) and G(D3) by a beta-1,4 linkage, resulting in the synthesis of G(M2) and G(D2), respectively.

REFERENCES

Chen, L.C., et al. Lung Cancer 67(2):216-220(2010) Boraska, V., et al. Clin. Biochem. 42(9):819-822(2009) Gornati, R., et al. Mol. Cell. Biochem. 298 (1-2), 59-68 (2007) : Li, J., et al. J. Biol. Chem. 275(52):41476-41486(2000) Li, J., et al. J. Biol. Chem. 275(52):41476-41486(2000)