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TBCK Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q8TEA7 |
| Other Accession | Q8BM85, NP_001156907.1 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 100679 Da |
| Antigen Region | 109-135 aa |
| Gene ID | 93627 |
|---|---|
| Other Names | TBC domain-containing protein kinase-like protein, TBCK {ECO:0000303|PubMed:12471243}, TBCKL |
| Target/Specificity | This TBCK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 109-135 amino acids from the N-terminal region of human TBCK. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | TBCK Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TBCK {ECO:0000303|PubMed:12471243} |
|---|---|
| Synonyms | TBCKL |
| Function | Involved in the modulation of mTOR signaling and expression of mTOR complex components (PubMed:27040691, PubMed:23977024). Involved in the regulation of cell proliferation and growth (PubMed:23977024, PubMed:24576458). Involved in the control of actin-cytoskeleton organization (PubMed:23977024). |
| Cellular Location | Cytoplasm. Cytoplasm, cytoskeleton, spindle. Midbody Note=Mainly localized in the cytoplasm during interphase. During metaphase, TBCK accumulates at the mitotic spindle. At the end of mitosis, it is detected at the midbody. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
The function of HSPC302 has not yet been determined.
References
Kalsi, G., et al. Hum. Mol. Genet. 19(12):2497-2506(2010)
Ishibashi, K., et al. Genes Cells 14(1):41-52(2009)
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