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METTL6 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q8TCB7 |
| Other Accession | NP_689609.2 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 33251 Da |
| Antigen Region | 168-195 aa |
| Gene ID | 131965 |
|---|---|
| Other Names | Methyltransferase-like protein 6, 211-, METTL6 |
| Target/Specificity | This METTL6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 168-195 amino acids from the Central region of human METTL6. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | METTL6 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | METTL6 {ECO:0000303|PubMed:32923617, ECO:0000312|HGNC:HGNC:28343} |
|---|---|
| Function | S-adenosyl-L-methionine-dependent methyltransferase that mediates N(3)-methylcytidine modification of residue 32 of the tRNA anticodon loop of tRNA(Ser), including tRNA(Ser)(UGA) and tRNA(Ser)(GCU) (PubMed:32923617, PubMed:34922197, PubMed:34268557, PubMed:34862464). Interaction with SARS1/SerRS is required for N(3)- methylcytidine methylation (PubMed:34268557). |
| Cellular Location | Cytoplasm. Nucleus |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Probable methyltransferase (By similarity).
References
McArdle, P.F., et al. Arthritis Rheum. 58(9):2874-2881(2008)
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