|Application ||WB, E|
|Other Accession||Q4R6Y5, NP_859061.3|
|Calculated MW||46958 Da|
|Antigen Region||111-138 aa|
|Other Names||Zinc/RING finger protein 4, RING finger protein 204, ZNRF4, RNF204|
|Target/Specificity||This ZNRF4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 111-138 amino acids from the N-terminal region of human ZNRF4.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ZNRF4 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||E3 ubiquitin-protein ligase which specifically induces ubiquitination and proteasomal degradation of CANX within the endoplasmic reticulum (PubMed:21205830). Could have a role in spermatogenesis (By similarity).|
|Cellular Location||Endoplasmic reticulum membrane; Single-pass type I membrane protein|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
ZNRF4 contains 1 PA (protease associated) domain and 1 RING-type zinc finger.
Grimwood, J., et al. Nature 428(6982):529-535(2004)
Fujii, T., et al. Genomics 57(1):94-101(1999)
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