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OCIAD1 Antibody (C-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - OCIAD1 Antibody (C-term) AP18379b
    OCIAD1 Antibody (C-term) (Cat. #AP18379b) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the OCIAD1 Antibody detected the OCIAD1 protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q9NX40
Other Accession Q5XIG4, Q5E948, NP_001073308.1
Reactivity Human
Predicted Bovine, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 27626 Da
Antigen Region 184-210 aa
Additional Information
Gene ID 54940
Other Names OCIA domain-containing protein 1, Ovarian carcinoma immunoreactive antigen, OCIAD1, OCIA
Target/Specificity This OCIAD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 184-210 amino acids from the C-terminal region of human OCIAD1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsOCIAD1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name OCIAD1 (HGNC:16074)
Function Maintains stem cell potency (By similarity). Increases STAT3 phosphorylation and controls ERK phosphorylation (By similarity). May act as a scaffold, increasing STAT3 recruitment onto endosomes (By similarity). Involved in integrin-mediated cancer cell adhesion and colony formation in ovarian cancer (PubMed:20515946).
Cellular Location Endosome {ECO:0000250|UniProtKB:Q9CRD0}.
Tissue Location Isoform 1 is highly expressed in many tissues, including testis, brain, placenta, ovary, prostate and mammary gland Isoform 2 expression is restricted to the central nervous system including brain, cerebellum and spinal cord
Research Areas
Citations (0)
citation

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Background

The function of this protein remains unknown.

References

Wang, C., et al. Mol. Cancer Ther. 9(6):1709-1718(2010)
Sengupta, S., et al. Gynecol. Oncol. 109(2):226-233(2008)
Kim, J.M., et al. DNA Res. 13(6):275-286(2006)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Oh, J.H., et al. Mamm. Genome 16(12):942-954(2005)

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$ 182.50
$ 70.00
Cat# AP18379b
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