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TRHR Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - TRHR Antibody (Center) AP18399c
    TRHR Antibody (Center) (Cat. #AP18399c) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the TRHR Antibody detected the TRHR protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P34981
Other Accession Q01717, NP_003292.1
Reactivity Human
Predicted Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 45085 Da
Antigen Region 209-238 aa
Additional Information
Gene ID 7201
Other Names Thyrotropin-releasing hormone receptor, TRH-R, Thyroliberin receptor, TRHR
Target/Specificity This TRHR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 209-238 amino acids from the Central region of human TRHR.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTRHR Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Receptor for thyrotropin-releasing hormone. This receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system.
Cellular Location Cell membrane; Multi-pass membrane protein.
Research Areas
Citations (0)

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Thyrotropin-releasing hormone (TRH; MIM 275120), a small neuropeptide, is widely distributed throughout the central and peripheral nervous system as well as in extraneural tissues. The peptide is synthesized in the hypothalamus and transported by the portal vascular system to the anterior pituitary where it acts on thyrotropic and lactotropic cells to promote secretion of TSH and prolactin, respectively. Thyrotropin-releasing hormone receptor is a G protein-coupled receptor that activates the inositol phospholipid-calcium-protein kinase C transduction pathway upon the binding of TRH. The TRHR gene is expressed in the thyrotrope cells of the anterior pituitary.


Gehret, A.U., et al. Biochem. J. 428(2):235-245(2010)
Gehret, A.U., et al. Mol. Pharmacol. 77(2):288-297(2010)
Zhu, C.C., et al. J. Biol. Chem. 277(31):28228-28237(2002)
Matre, V., et al. J. Neurochem. 72(1):40-50(1999)
Iwasaki, T., et al. J. Biol. Chem. 271(36):22183-22188(1996)

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$ 295.00
$ 99.00
Cat# AP18399c
(40 western blots)
Availability: In Stock
Bulk Size
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