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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   EDA2R Antibody (C-term)   

EDA2R Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - EDA2R Antibody (C-term) AP18402b
    EDA2R Antibody (C-term) (Cat. #AP18402b) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the EDA2R Antibody detected the EDA2R protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9HAV5
Other Accession NP_068555.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 32759 Da
Antigen Region 267-297 aa
Additional Information
Gene ID 60401
Other Names Tumor necrosis factor receptor superfamily member 27, X-linked ectodysplasin-A2 receptor, EDA-A2 receptor, EDA2R, TNFRSF27, XEDAR
Target/Specificity This EDA2R antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 267-297 amino acids from the C-terminal region of human EDA2R.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsEDA2R Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name EDA2R
Synonyms TNFRSF27, XEDAR
Function Receptor for EDA isoform A2, but not for EDA isoform A1. Mediates the activation of the NF-kappa-B and JNK pathways. Activation seems to be mediated by binding to TRAF3 and TRAF6.
Cellular Location Membrane; Single-pass type III membrane protein
Research Areas
Citations (0)

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EDA-A1 and EDA-A2 are two isoforms of ectodysplasin that are encoded by the anhidrotic ectodermal dysplasia (EDA) gene. Mutations in EDA give rise to a clinical syndrome characterized by loss of hair, sweat glands, and teeth. The protein encoded by this gene specifically binds to EDA-A2 isoform. This protein is a type III transmembrane protein of the TNFR (tumor necrosis factor receptor) superfamily, and contains 3 cysteine-rich repeats and a single transmembrane domain but lacks an N-terminal signal peptide. Multiple alternatively spliced transcript variants have been found for this gene, but some variants lack sufficient support. [provided by RefSeq].


Brockschmidt, F.F., et al. Br. J. Dermatol. 162(4):899-903(2010)
Tanikawa, C., et al. Oncogene 28(34):3081-3092(2009)
Fujimoto, A., et al. J. Hum. Genet. 54(8):461-465(2009)
Hillmer, A.M., et al. Hum. Genet. 126(2):255-264(2009)
Richards, J.B., et al. Nat. Genet. 40(11):1282-1284(2008)

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$ 295.00
$ 99.00
Cat# AP18402b
(40 western blots)
Availability: In Stock
Bulk Size
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