|Application ||WB, E|
|Calculated MW||33982 Da|
|Antigen Region||243-272 aa|
|Other Names||PDZ domain-containing protein GIPC3, GIPC3, C19orf64|
|Target/Specificity||This GIPC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 243-272 amino acids from the C-terminal region of human GIPC3.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||GIPC3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Required for postnatal maturation of the hair bundle and long-term survival of hair cells and spiral ganglion.|
|Tissue Location||Widely expressed in adult and fetal tissues. Highest levels are found in jejunum, lymph node, parietal lobe, fetal spleen and fetal thymus. Expressed in cervical, melanoma, chronic myelogenous and gastric cancer cell lines|
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Provided below are standard protocols that you may find useful for product applications.
GIPC3 is widely expressed in adult and fetal tissues. Highest levels are found in jejunum, lymph node, parietal lobe, fetal spleen and fetal thymus. It is expressed in cervical, melanoma, chronic myelogenous and gastric cancer cell lines.
Vega, A., et al. Gynecol. Oncol. 112(1):210-214(2009)
Matsuoka, S., et al. Science 316(5828):1160-1166(2007)
Grimwood, J., et al. Nature 428(6982):529-535(2004)
Katoh, M. Int. J. Mol. Med. 9(6):585-589(2002)
Saitoh, T., et al. Int. J. Oncol. 20(3):577-582(2002)
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