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ALKBH5 Antibody (Center)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AP18410c | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP18410c-ev20 | 20 ug 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
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ALKBH5 Antibody (Center) - Product info | |
| Application | WB
|
| Primary Accession | Q6P6C2 |
| Other Accession | D3ZKD3, Q3TSG4, E1BH29, NP_060228.3 |
| Reactivity | Human |
| Predicted | Bovine, Mouse, Rat |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 44256 Da |
ALKBH5 Antibody (Center) - Additional info | |
| Gene ID 54890 | |
| Other Names ALKBH5; ABH5; OFOXD1; Probable alpha-ketoglutarate-dependent dioxygenase ABH5; Alkylated DNA repair protein alkB homolog 5 | |
| Target/Specificity This ALKBH5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 301-330 amino acids from the Central region of human ALKBH5. | |
| Dilution WB~~1:100~500WB~~1:1000 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions ALKBH5 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. | |
ALKBH5 Antibody (Center) - Protein Information | |
| Name ALKBH5 | |
| Synonyms ABH5, OFOXD1 | |
| Function Dioxygenase that demethylates RNA by oxidative demethylation: specifically demethylates N(6)-methyladenosine (m(6)A) RNA, the most prevalent internal modification of messenger RNA (mRNA) in higher eukaryotes. Requires molecular oxygen, alpha- ketoglutarate and iron. Demethylation of m(6)A mRNA affects mRNA processing and export and is required for spermatogenesis | |
| Cellular Location Nucleus speckle. | |
| Tissue Location Widely expressed, with highest expression in lung, followed by testis, pancreas, spleen and ovary | |
ALKBH5 Antibody (Center) - Related products
ALKBH5 Antibody (Center) - Application data
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ALKBH5 Antibody (Center) (Cat. #AP18410c) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the ALKBH5 Antibody detected the ALKBH5 protein (arrow).
ALKBH5 Antibody (Center) - Research Areas
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BACKGROUND
Probable dioxygenase that requires molecular oxygen, alpha-ketoglutarate and iron (By similarity).
REFERENCES
Olsen, J.V., et al. Cell 127(3):635-648(2006) Bi, W., et al. Genome Res. 12(5):713-728(2002)
