|Application ||WB, E|
|Other Accession||P0CG33, A6NDK9, A6NDN3, NP_001033729.2|
|Calculated MW||79946 Da|
|Antigen Region||516-543 aa|
|Other Names||Golgin subfamily A member 6A, Golgin linked to PML, Golgin-like protein, GOLGA6A, GLP, GOLGA6|
|Target/Specificity||This GOLGA6A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 516-543 amino acids from the C-terminal region of human GOLGA6A.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||GOLGA6A Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Tissue Location||Highly expressed in seminiferous tubes in testis. Highly expressed in spermatids, barely detectable in late pachytene spermatocytes, and not detectable in spermatogonia Detected at intermediate levels in pancreas and lymph nodes, and at much lower levels in spleen, peripheral blood leukocytes, skeletal muscle, liver, lung, placenta, brain and heart|
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Provided below are standard protocols that you may find useful for product applications.
The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory pathway, consists of a series of stacked cisternae (flattened membrane sacs). Interactions between the Golgi and microtubules are thought to be important for the reorganization of the Golgi after it fragments during mitosis. The protein encoded by this gene is a member of the golgin family of proteins, whose members localize to the Golgi. This gene is found in a large, low copy repeat sequence or duplicon that is found in multiple copies, that are greather than 90% similar, on chromosome 15. Duplicons are associated with deletions, inversions and other chromosome rearrangements that underlie genomic disease. The protein encoded by this gene is thought to be a functional golgin protein while the majority of the related copies of this gene are thought to be transcribed pseudogenes.
Ventura, M., et al. Genome Res. 13(9):2059-2068(2003)
Pujana, M.A., et al. Eur. J. Hum. Genet. 10(1):26-35(2002)
Gratacos, M., et al. Cell 106(3):367-379(2001)
Pujana, M.A., et al. Genome Res. 11(1):98-111(2001)
Gilles, F., et al. Genomics 70(3):364-374(2000)
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