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GOLGA6A Antibody (C-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - GOLGA6A Antibody (C-term) AP18412B
    GOLGA6A Antibody (C-term) (Cat. #AP18412b) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the GOLGA6A Antibody detected the GOLGA6A protein (arrow).
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  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q9NYA3
Other Accession P0CG33, A6NDK9, A6NDN3, NP_001033729.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 79946 Da
Antigen Region 516-543 aa
Additional Information
Gene ID 342096
Other Names Golgin subfamily A member 6A, Golgin linked to PML, Golgin-like protein, GOLGA6A, GLP, GOLGA6
Target/Specificity This GOLGA6A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 516-543 amino acids from the C-terminal region of human GOLGA6A.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGOLGA6A Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GOLGA6A
Synonyms GLP, GOLGA6
Tissue Location Highly expressed in seminiferous tubes in testis. Highly expressed in spermatids, barely detectable in late pachytene spermatocytes, and not detectable in spermatogonia. Detected at intermediate levels in pancreas and lymph nodes, and at much lower levels in spleen, peripheral blood leukocytes, skeletal muscle, liver, lung, placenta, brain and heart
Research Areas
Citations (0)
citation

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Background

The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory pathway, consists of a series of stacked cisternae (flattened membrane sacs). Interactions between the Golgi and microtubules are thought to be important for the reorganization of the Golgi after it fragments during mitosis. The protein encoded by this gene is a member of the golgin family of proteins, whose members localize to the Golgi. This gene is found in a large, low copy repeat sequence or duplicon that is found in multiple copies, that are greather than 90% similar, on chromosome 15. Duplicons are associated with deletions, inversions and other chromosome rearrangements that underlie genomic disease. The protein encoded by this gene is thought to be a functional golgin protein while the majority of the related copies of this gene are thought to be transcribed pseudogenes.

References

Ventura, M., et al. Genome Res. 13(9):2059-2068(2003)
Pujana, M.A., et al. Eur. J. Hum. Genet. 10(1):26-35(2002)
Gratacos, M., et al. Cell 106(3):367-379(2001)
Pujana, M.A., et al. Genome Res. 11(1):98-111(2001)
Gilles, F., et al. Genomics 70(3):364-374(2000)

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$ 365.00
$ 140.00
Cat# AP18412B
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