|Application ||WB, E|
|Calculated MW||46317 Da|
|Antigen Region||162-190 aa|
|Other Names||Solute carrier family 52, riboflavin transporter, member 1, Porcine endogenous retrovirus A receptor 2, PERV-A receptor 2, Protein GPR172B, Riboflavin transporter 1, hRFT1, SLC52A1, GPR172B, PAR2, RFT1|
|Target/Specificity||This GPR172B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 162-190 amino acids from the Central region of human GPR172B.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||GPR172B Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||GPR172B, PAR2, RFT1|
|Function||Riboflavin transporter. Riboflavin transport is Na(+)- independent but moderately pH-sensitive. Activity is strongly inhibited by riboflavin analogs, such as lumiflavin. Weakly inhibited by flavin adenine dinucleotide (FAD). In case of infection by retroviruses, acts as a cell receptor to retroviral envelopes similar to the porcine endogenous retrovirus (PERV-A).|
|Cellular Location||Cell membrane; Multi-pass membrane protein|
|Tissue Location||Widely expressed. Highly expressed in the testis, placenta and small intestine. Expressed at lower level in other tissues.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
GPCR41 (MIM 607882) and GPCR42 act as receptors for porcine endogenous retrovirus subgroup A (PERV-A).[supplied by OMIM].
Yonezawa, A., et al. Am. J. Physiol., Cell Physiol. 295 (3), C632-C641 (2008) :
Ericsson, T.A., et al. Proc. Natl. Acad. Sci. U.S.A. 100(11):6759-6764(2003)
Takeda, S., et al. FEBS Lett. 520 (1-3), 97-101 (2002) :
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