|Application ||WB, E|
|Calculated MW||43426 Da|
|Antigen Region||1-30 aa|
|Other Names||Methyltransferase-like protein 2B, 211-, METTL2B|
|Target/Specificity||This METTL2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human METTL2B.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||METTL2B Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Probable S-adenosyl-L-methionine-dependent methyltransferase that mediates 3-methylcytidine modification of some tRNAs.|
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Provided below are standard protocols that you may find useful for product applications.
This gene is a member of a family of methyltransferases that share homology with, but are distinct from, the UbiE family of methyltransferases. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.
Zody, M.C., et al. Nature 440(7087):1045-1049(2006)
Zhang, S.X., et al. Gene 280 (1-2), 135-144 (2001) :
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