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METTL2B Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q6P1Q9 |
| Other Accession | NP_060866.2 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 43426 Da |
| Antigen Region | 1-30 aa |
| Gene ID | 55798 |
|---|---|
| Other Names | Methyltransferase-like protein 2B, 211-, METTL2B |
| Target/Specificity | This METTL2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human METTL2B. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | METTL2B Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | METTL2B {ECO:0000303|PubMed:28655767, ECO:0000312|HGNC:HGNC:18272} |
|---|---|
| Function | S-adenosyl-L-methionine-dependent methyltransferase that mediates N(3)-methylcytidine modification of residue 32 of the tRNA anticodon loop of tRNA(Thr)(UGU) and tRNA(Arg)(CCU). |
| Cellular Location | Cytoplasm. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene is a member of a family of methyltransferases that share homology with, but are distinct from, the UbiE family of methyltransferases. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.
References
Zody, M.C., et al. Nature 440(7087):1045-1049(2006)
Zhang, S.X., et al. Gene 280 (1-2), 135-144 (2001) :
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