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PKNOX2 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q96KN3 |
| Other Accession | Q8BG99, NP_071345.2 |
| Reactivity | Human |
| Predicted | Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 52028 Da |
| Antigen Region | 298-324 aa |
| Other Names | Homeobox protein PKNOX2, Homeobox protein PREP-2, PBX/knotted homeobox 2, PKNOX2, PREP2 |
|---|---|
| Target/Specificity | This PKNOX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 298-324 amino acids from the Central region of human PKNOX2. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | PKNOX2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | PKNOX2 |
|---|---|
| Synonyms | PREP2 |
| Cellular Location | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108, ECO:0000269|PubMed:11549286} |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Homeodomain proteins are sequence-specific transcription factors that share a highly conserved DNA-binding domain and play fundamental roles in cell proliferation, differentiation, and death. PKNOX2 belongs to the TALE (3-amino acid loop extension) class of homeodomain proteins characterized by a 3-amino acid extension between alpha helices 1 and 2 within the homeodomain (Imoto et al., 2001 [PubMed 11549286]).
References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Chen, X., et al. Proc. Natl. Acad. Sci. U.S.A. (2009) In press :
Haller, K., et al. J. Biol. Chem. 279(47):49384-49394(2004)
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