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CGGBP1 Antibody (C-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - CGGBP1 Antibody (C-term) AP18438b
    CGGBP1 Antibody (C-term) (Cat. #AP18438b) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the CGGBP1 Antibody detected the CGGBP1 protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q9UFW8
Other Accession Q8BHG9, NP_001008391.1
Reactivity Human
Predicted Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 18820 Da
Antigen Region 126-152 aa
Additional Information
Gene ID 8545
Other Names CGG triplet repeat-binding protein 1, CGG-binding protein 1, 20 kDa CGG-binding protein, p20-CGGBP DNA-binding protein, CGGBP1, CGGBP
Target/Specificity This CGGBP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 126-152 amino acids from the C-terminal region of human CGGBP1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCGGBP1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CGGBP1
Synonyms CGGBP
Function Binds to nonmethylated 5'-d(CGG)(n)-3' trinucleotide repeats in the FMR1 promoter. May play a role in regulating FMR1 promoter.
Cellular Location Nucleus.
Tissue Location Ubiquitous. Highly expressed in placenta, thymus, lymph nodes, cerebellum and cerebral cortex. Low expression in other regions of the brain.
Citations (0)
citation

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Background

CGGBP1 influences expression of the FMR1 gene (MIM 309550), which is associated with the fragile X mental retardation syndrome (MIM 300624), by specifically interacting with the 5-prime (CGG)n-3-prime repeat in its 5-prime UTR.

References

Gulyi, P.V., et al. Tsitologiia 51(12):1005-1012(2009)
Arrieta, I., et al. Hum. Biol. 80(6):593-600(2008)
Matsuoka, S., et al. Science 316(5828):1160-1166(2007)
Naumann, F., et al. Genomics 83(1):106-118(2004)
Chen, L.S., et al. Hum. Mol. Genet. 12(23):3067-3074(2003)

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$ 182.50
$ 70.00
Cat# AP18438b
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