|Application ||WB, E|
|Calculated MW||55184 Da|
|Antigen Region||457-483 aa|
|Other Names||Glycogenin-2, GN-2, GN2, GYG2|
|Target/Specificity||This GYG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 457-483 amino acids from the C-terminal region of human GYG2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||GYG2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Self-glucosylates, via an inter-subunit mechanism, to form an oligosaccharide primer that serves as substrate for glycogen synthase.|
|Tissue Location||Expressed preferentially in liver, heart, and pancreas|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the the glycogenin family. Glycogenin is a self-glucosylating protein involved in the initiation reactions of glycogen biosynthesis. A gene on chromosome 3 encodes the muscle glycogenin and this X-linked gene encodes the glycogenin mainly present in liver; both are involved in blood glucose homeostasis. This gene has a short version on chromosome Y, which is 3' truncated and can not make a functional protein. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
Gibbons, B.J., et al. J. Mol. Biol. 319(2):463-477(2002)
Harris, R.A., et al. Proteomics 2(2):212-223(2002)
Zhai, L., et al. Gene 242 (1-2), 229-235 (2000) :
Mu, J., et al. J. Biol. Chem. 273(52):34850-34856(1998)
Orho, M., et al. J. Clin. Invest. 102(3):507-515(1998)
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