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GCNT2 Antibody (Center)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AP18452c | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP18452c-ev20 | 20 ug 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
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GCNT2 Antibody (Center) - Product info | |
| Application | WB
|
| Primary Accession | Q8N0V5 |
| Other Accession | NP_663624.1 |
| Reactivity | Human |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 45873 Da |
GCNT2 Antibody (Center) - Additional info | |
| Gene ID 2651 | |
| Other Names GCNT2; GCNT5; II; NACGT1; N-acetyllactosaminide beta-1, 6-N-acetylglucosaminyl-transferase, isoform A; I-branching enzyme; IGNT | |
| Target/Specificity This GCNT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 212-240 amino acids from the Central region of human GCNT2. | |
| Dilution WB~~1:100~500WB~~1:1000 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions GCNT2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. | |
GCNT2 Antibody (Center) - Protein Information | |
| Name GCNT2 | |
| Synonyms GCNT5, II, NACGT1 | |
| Function Branching enzyme that converts linear into branched poly-N-acetyllactosaminoglycans. Introduces the blood group I antigen during embryonic development. It is closely associated with the development and maturation of erythroid cells. The expression of the blood group I antigen in erythrocytes is determined by isoform C | |
| Cellular Location Golgi apparatus membrane; Single-pass type II membrane protein (By similarity) | |
| Tissue Location Isoform B is expressed in lens epithelium cells. Isoform C is expressed in reticulocytes | |
GCNT2 Antibody (Center) - Related products
AP10215b: GCNT2 Antibody (C-term)
AP18452c: GCNT2 Antibody (Center)
DC14682: Human GCNT2 cDNA Clone
GCNT2 Antibody (Center) - Application data
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GCNT2 Antibody (Center) (Cat. #AP18452c) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the GCNT2 Antibody detected the GCNT2 protein (arrow).
GCNT2 Antibody (Center) - Research Areas
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BACKGROUND
This gene encodes the enzyme responsible for formation of the blood group I antigen. The i and I antigens are distinguished by linear and branched poly-N-acetyllactosaminoglycans, respectively. The encoded protein is the I-branching enzyme, a beta-1,6-N-acetylglucosaminyltransferase responsible for the conversion of fetal i antigen to adult I antigen in erythrocytes during embryonic development. Mutations in this gene have been associated with adult i blood group phenotype. Alternatively spliced transcript variants encoding different isoforms have been described.
REFERENCES
Twu, Y.C., et al. Blood 110(13):4526-4534(2007) Wang, L., et al. Biochem. Biophys. Res. Commun. 331(4):958-963(2005) Pras, E., et al. Invest. Ophthalmol. Vis. Sci. 45(6):1940-1945(2004) Inaba, N., et al. Blood 101(7):2870-2876(2003) Yu, L.C., et al. Blood 101(6):2081-2088(2003)
