|Application ||WB, E|
|Other Accession||Q9JI74, NP_065917|
|Calculated MW||82680 Da|
|Antigen Region||1-30 aa|
|Other Names||Kelch-like protein 1, KLHL1, KIAA1490|
|Target/Specificity||This KLHL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human KLHL1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||KLHL1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May play a role in organizing the actin cytoskeleton of the brain cells.|
|Cellular Location||Cytoplasm, cytoskeleton.|
|Tissue Location||Highly expressed in brain.|
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Provided below are standard protocols that you may find useful for product applications.
The KLHL1 protein belongs to a family of actin-organizing proteins related to Drosophila Kelch (Nemes et al., 2000 [PubMed 10888605]).
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Aromolaran, K.A., et al. Am. J. Physiol., Cell Physiol. 298 (6), C1353-C1362 (2010) :
Chen, W.L., et al. Brain Res. 1233, 176-184 (2008) :
Aromolaran, K.A., et al. Neuroscience 145(3):841-850(2007)
Seng, S., et al. Mol. Cell. Biol. 26(22):8371-8384(2006)
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