|Application ||WB, E|
|Calculated MW||76764 Da|
|Antigen Region||132-159 aa|
|Other Names||Tensin-4, C-terminal tensin-like protein, TNS4, CTEN|
|Target/Specificity||This CTEN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 132-159 amino acids from the N-terminal region of human CTEN.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CTEN Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May be involved in cell migration, cartilage development and in linking signal transduction pathways to the cytoskeleton (By similarity). May promote apoptosis, via its cleavage by caspase-3.|
|Cellular Location||Cell junction, focal adhesion. Cytoplasm, cytoskeleton|
|Tissue Location||Prostate and placenta. Down regulated in prostate cancer.|
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Provided below are standard protocols that you may find useful for product applications.
TNS4 may be involved in cell migration, cartilage development and in linking signal transduction pathways to the cytoskeleton (By similarity). May promote apoptosis, via its cleavage by caspase-3.
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Li, Y., et al. Prostate 70(1):48-60(2010)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Liao, Y.C., et al. Cancer Res. 69(11):4563-4566(2009)
Martuszewska, D., et al. PLoS ONE 4 (2), E4350 (2009) :
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