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RRBP1 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
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- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9P2E9 |
| Other Accession | NP_004578.2 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 152456 Da |
| Antigen Region | 1327-1355 aa |
| Gene ID | 6238 |
|---|---|
| Other Names | Ribosome-binding protein 1, 180 kDa ribosome receptor homolog, RRp, ES/130-related protein, Ribosome receptor protein, RRBP1, KIAA1398 |
| Target/Specificity | This RRBP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1327-1355 amino acids from the C-terminal region of human RRBP1. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | RRBP1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | RRBP1 |
|---|---|
| Synonyms | KIAA1398 |
| Function | Acts as a ribosome receptor and mediates interaction between the ribosome and the endoplasmic reticulum membrane. |
| Cellular Location | Endoplasmic reticulum membrane; Single-pass type III membrane protein |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Analysis of cDNA clones indicates that ribosome binding protein 1 may exist in different forms due to removal of tandem repeats, or partial intraexonic splicing of RRBP1. The form presented here is lacking the canine p180 ribosome-binding domain, NQGKKAEGAQ, which is tandemly repeated close to the N-terminus in other forms that haven't been fully characterized. RRBP1 has been excluded as a candidate gene in the cause of Alagille syndrome. Alternate splicing results in multiple transcript variants.
References
Ueno, T., et al. J. Biol. Chem. 285(39):29941-29950(2010)
Ueno, T., et al. Exp. Cell Res. 316(3):329-340(2010)
Krasnov, G.S., et al. Mol. Biol. (Mosk.) 43(2):348-356(2009)
Benyamini, P., et al. Mol. Biol. Cell 20(2):732-744(2009)
Bai, J.Z., et al. Cell Biol. Int. 32(5):473-483(2008)
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