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>   home   >   Products   >   Primary Antibodies   >   Immunology   >   IL34 Antibody (N-term)   

IL34 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - IL34 Antibody (N-term) AP18473a
    IL34 Antibody (N-term) (Cat. #AP18473a) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the IL34 antibody detected the IL34 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q6ZMJ4
Other Accession NP_001166242.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 27482 Da
Antigen Region 27-53 aa
Additional Information
Gene ID 146433
Other Names Interleukin-34, IL-34, IL34, C16orf77
Target/Specificity This IL34 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 27-53 amino acids from the N-terminal region of human IL34.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsIL34 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name IL34
Synonyms C16orf77
Function Cytokine that promotes the proliferation, survival and differentiation of monocytes and macrophages. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, and in the regulation of bone resorption. Signaling via CSF1R and its downstream effectors stimulates phosphorylation of MAPK1/ERK2 AND MAPK3/ERK1.
Cellular Location Secreted.
Tissue Location Detected in the sinusoidal epithelium in the red pulp of spleen (at protein level). Predominantly expressed in spleen. Also detected in a range of other tissues including heart, brain, lung, liver, kidney, thymus, testis, ovary, small intestine, prostate and colon.
Research Areas
Citations (0)

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Interleukin-34 is a cytokine that promotes the differentiation and viability of monocytes and macrophages through the colony-stimulating factor-1 receptor (CSF1R; MIM 164770) (Lin et al., 2008 [PubMed 18467591]).


Wei, S., et al. J. Leukoc. Biol. 88(3):495-505(2010)
Lin, H., et al. Science 320(5877):807-811(2008)
Lim, J., et al. Cell 125(4):801-814(2006)

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$ 295.00
$ 99.00
Cat# AP18473a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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