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KCNE4 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - KCNE4 Antibody (Center) AP18476c
    KCNE4 Antibody (Center) (Cat. #AP18476c) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the KCNE4 antibody detected the KCNE4 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8WWG9
Other Accession Q9WTW3, NP_542402.2
Reactivity Human
Predicted Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 23806 Da
Antigen Region 58-86 aa
Additional Information
Gene ID 23704
Other Names Potassium voltage-gated channel subfamily E member 4, MinK-related peptide 3, Minimum potassium ion channel-related peptide 3, Potassium channel subunit beta MiRP3, KCNE4
Target/Specificity This KCNE4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 58-86 amino acids from the Central region of human KCNE4.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsKCNE4 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name KCNE4
Function Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. May associate with KCNQ1/KVLTQ1 and inhibit potassium current.
Cellular Location Membrane; Single-pass membrane protein
Tissue Location Predominantly expressed in embryo and adult uterus. Low expression found in kidney, small intestine, lung and heart.
Research Areas
Citations (0)

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Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, isk-related subfamily. This member is a type I membrane protein, and a beta subunit that assembles with a potassium channel alpha-subunit to modulate the gating kinetics and enhance stability of the multimeric complex. This gene is prominently expressed in the embryo and in adult uterus.


Levy, D.I., et al. J. Physiol. (Lond.) 588 (PT 14), 2657-2668 (2010) :
Sole, L., et al. J. Cell. Sci. 122 (PT 20), 3738-3748 (2009) :
Trevino, L.R., et al. Nat. Genet. 41(9):1001-1005(2009)
Manderfield, L.J., et al. J. Physiol. (Lond.) 587 (PT 2), 303-314 (2009) :
Levy, D.I., et al. Am. J. Physiol. Renal Physiol. 295 (2), F380-F387 (2008) :

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$ 295.00
$ 99.00
Cat# AP18476c
(40 western blots)
Availability: In Stock
Bulk Size
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