|Application ||WB, E|
|Calculated MW||86344 Da|
|Antigen Region||725-753 aa|
|Other Names||Conserved oligomeric Golgi complex subunit 7, COG complex subunit 7, Component of oligomeric Golgi complex 7, COG7|
|Target/Specificity||This COG7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 725-753 amino acids from the C-terminal region of human COG7.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||COG7 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Required for normal Golgi function.|
|Cellular Location||Golgi apparatus membrane; Peripheral membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene resides in the golgi, and constitutes one of the 8 subunits of the conserved oligomeric Golgi (COG) complex, which is required for normal golgi morphology and localization. Mutations in this gene are associated with the congenital disorder of glycosylation type IIe.
Zeevaert, R., et al. Eur J Med Genet 52(5):303-305(2009)
Laufman, O., et al. EMBO J. 28(14):2006-2017(2009)
Morava, E., et al. Eur. J. Hum. Genet. 15(6):638-645(2007)
Steet, R., et al. Mol. Biol. Cell 17(5):2312-2321(2006)
Shestakova, A., et al. Traffic 7(2):191-204(2006)
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