|Application ||WB, E|
|Calculated MW||98556 Da|
|Antigen Region||458-485 aa|
|Other Names||Prostaglandin F2 receptor negative regulator, CD9 partner 1, CD9P-1, Glu-Trp-Ile EWI motif-containing protein F, EWI-F, Prostaglandin F2-alpha receptor regulatory protein, Prostaglandin F2-alpha receptor-associated protein, CD315, PTGFRN, CD9P1, EWIF, FPRP, KIAA1436|
|Target/Specificity||This PTGFRN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 458-485 amino acids from the Central region of human PTGFRN.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||PTGFRN Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||CD9P1, EWIF, FPRP, KIAA1436|
|Function||Inhibits the binding of prostaglandin F2-alpha (PGF2- alpha) to its specific FP receptor, by decreasing the receptor number rather than the affinity constant. Functional coupling with the prostaglandin F2-alpha receptor seems to occur (By similarity).|
|Cellular Location||Endoplasmic reticulum membrane; Single-pass type I membrane protein Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
PTGFRN inhibits the binding of prostaglandin F2-alpha (PGF2-alpha) to its specific FP receptor, by decreasing the receptor number rather than the affinity constant. Functional coupling with the prostaglandin F2-alpha receptor seems to occur (By similarity).
Ikeda, M., et al. Biol. Psychiatry 67(3):263-269(2010)
Andre, M., et al. J Proteomics 73(1):93-102(2009)
Andre, M., et al. Proteomics 7(21):3880-3895(2007)
Abache, T., et al. J. Cell. Biochem. 102(3):650-664(2007)
Sala-Valdes, M., et al. J. Biol. Chem. 281(28):19665-19675(2006)
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