|Application ||WB, E|
|Calculated MW||72732 Da|
|Antigen Region||435-462 aa|
|Other Names||E3 ubiquitin-protein ligase ZSWIM2, 632-, MEKK1-related protein X, MEX, ZZ-type zinc finger-containing protein 2, Zinc finger SWIM domain-containing protein 2, ZSWIM2, ZZZ2|
|Target/Specificity||This ZSWIM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 435-462 amino acids from the C-terminal region of human ZSWIM2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ZSWIM2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||E3 ubiquitin-protein ligase involved in the regulation of Fas-, DR3- and DR4-mediated apoptosis. Functions in conjunction with the UBE2D1, UBE2D3 and UBE2E1 E2 ubiquitin-conjugating enzymes.|
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Provided below are standard protocols that you may find useful for product applications.
E3 ubiquitin-protein ligase involved in the regulation of Fas-, DR3-and DR4-mediated apoptosis. Functions in conjunction with the UBE2D1, UBE2D3 and UBE2E1 E2 ubiquitin-conjugating enzymes (By similarity).
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Yoshida, T., et al. Int. J. Mol. Med. 25(4):649-656(2010)
Oguri, M., et al. Am. J. Hypertens. 23(1):70-77(2010)
Nishito, Y., et al. Biochem. J. 396(3):411-417(2006)
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