PCMTD2 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | Q9NV79 |
Other Accession | Q58CZ2, NP_001098395.1 |
Reactivity | Human |
Predicted | Bovine |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 41072 Da |
Antigen Region | 251-278 aa |
Gene ID | 55251 |
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Other Names | Protein-L-isoaspartate O-methyltransferase domain-containing protein 2, PCMTD2, C20orf36 |
Target/Specificity | This PCMTD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 251-278 amino acids from the C-terminal region of human PCMTD2. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | PCMTD2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | PCMTD2 |
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Synonyms | C20orf36 |
Function | May act as a substrate recognition component of an ECS (Elongin BC-CUL5-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. May bind to the methyltransferase cofactor S- adenosylmethionine (AdoMet) via the N-terminal AdoMet binding motif, but probably does not display methyltransferase activity. |
Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:P22061}. |
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Provided below are standard protocols that you may find useful for product applications.
Background
PCMTD2 belongs to the L-isoaspartyl/D-aspartyl protein methyltransferase family. There are 3 named isoforms produced by alternative splicing.
References
Deloukas, P., et al. Nature 414(6866):865-871(2001)
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