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PCMTD2 Antibody (C-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - PCMTD2 Antibody (C-term) AP18507b
    PCMTD2 Antibody (C-term) (Cat. #AP18507b) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the PCMTD2 antibody detected the PCMTD2 protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q9NV79
Other Accession Q58CZ2, NP_001098395.1
Reactivity Human
Predicted Bovine
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 41072 Da
Antigen Region 251-278 aa
Additional Information
Gene ID 55251
Other Names Protein-L-isoaspartate O-methyltransferase domain-containing protein 2, PCMTD2, C20orf36
Target/Specificity This PCMTD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 251-278 amino acids from the C-terminal region of human PCMTD2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPCMTD2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PCMTD2
Synonyms C20orf36
Function May act as a substrate recognition component of an ECS (Elongin BC-CUL5-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. May bind to the methyltransferase cofactor S- adenosylmethionine (AdoMet) via the N-terminal AdoMet binding motif, but probably does not display methyltransferase activity.
Cellular Location Cytoplasm {ECO:0000250|UniProtKB:P22061}.
Research Areas
Citations (0)
citation

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Background

PCMTD2 belongs to the L-isoaspartyl/D-aspartyl protein methyltransferase family. There are 3 named isoforms produced by alternative splicing.

References

Deloukas, P., et al. Nature 414(6866):865-871(2001)

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$ 365.00
$ 140.00
Cat# AP18507b
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