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PGLYRP4 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - PGLYRP4 Antibody (Center) AP18508c
    Anti-PGLYRP4 Antibody (Center) at 1:1000 dilution + HACAT whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 41 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • WB - PGLYRP4 Antibody (Center) AP18508c
    PGLYRP4 Antibody (Center) (Cat. #AP18508c) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the PGLYRP4 antibody detected the PGLYRP4 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q96LB8
Other Accession NP_065126.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 40620 Da
Antigen Region 242-268 aa
Additional Information
Gene ID 57115
Other Names Peptidoglycan recognition protein 4, Peptidoglycan recognition protein I-beta, PGLYRPIbeta, PGRP-I-beta, Peptidoglycan recognition protein intermediate beta, PGLYRP4, PGRPIB
Target/Specificity This PGLYRP4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 242-268 amino acids from the Central region of human PGLYRP4.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPGLYRP4 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms PGRPIB
Function Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram- negative bacteria, and has bacteriostatic activity towards Gram- negative bacteria. Plays a role in innate immunity.
Cellular Location Secreted.
Tissue Location Detected in skin epidermis, eccrine sweat glands and ducts, mucous cells in the submandibular salivary gland, mucous cells in the throat, ciliary body epithelial cells of the eye, small intestine, colon, stomach and in mature epithelial cells of the tongue (at protein level). High expression in skin and esophagus. Expressed also to a much lesser extent in the tonsils and thymus.
Research Areas
Citations (0)

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Peptidoglycan recognition proteins, such as PGRPI-beta, are part of the innate immune system and recognize peptidoglycan, a ubiquitous component of bacterial cell walls.


Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Cho, S., et al. Proc. Natl. Acad. Sci. U.S.A. 104(21):8761-8766(2007)
Lu, X., et al. J. Biol. Chem. 281(9):5895-5907(2006)
Sun, C., et al. Hum. Genet. 119 (1-2), 113-125 (2006) :

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$ 295.00
$ 99.00
Cat# AP18508c
(40 western blots)
Availability: In Stock
Bulk Size
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