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RANBP17 Antibody (N-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - RANBP17 Antibody (N-term) AP18509A
    RANBP17 Antibody (N-term) (Cat. #AP18509a) western blot analysis in mouse testis tissue lysates (35ug/lane).This demonstrates the RANBP17 antibody detected the RANBP17 protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q9H2T7
Other Accession Q99NF8, NP_075048.1
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 124375 Da
Antigen Region 149-175 aa
Additional Information
Gene ID 64901
Other Names Ran-binding protein 17, RANBP17
Target/Specificity This RANBP17 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 149-175 amino acids from the N-terminal region of human RANBP17.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsRANBP17 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RANBP17
Function May function as a nuclear transport receptor.
Cellular Location Cytoplasm. Nucleus. Nucleus, nuclear pore complex
Tissue Location Highly expressed in testis, moderately in pancreas and weakly in other tissues studied.
Research Areas
Citations (0)
citation

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Background

The transport of protein and large RNAs through the nuclear pore complexes (NPC) is an energy-dependent and regulated process. The import of proteins with a nuclear localization signal (NLS) is accomplished by recognition of one or more clusters of basic amino acids by the importin-alpha/beta complex; see MIM 600685 and MIM 602738. The small GTPase RAN (MIM 601179) plays a key role in NLS-dependent protein import. RAN-binding protein-17 is a member of the importin-beta superfamily of nuclear transport receptors.

References

Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Kutay, U., et al. J. Biol. Chem. 275(51):40163-40168(2000)
Koch, P., et al. Biochem. Biophys. Res. Commun. 278(1):241-249(2000)

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$ 365.00
$ 140.00
Cat# AP18509A
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