|Application ||WB, E|
|Calculated MW||68772 Da|
|Antigen Region||250-279 aa|
|Other Names||FERM domain-containing protein 3, Band 41-like protein 4O, Ovary type protein 41, 41O, FRMD3, EPB41L4O|
|Target/Specificity||This FRMD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 250-279 amino acids from the Central region of human FRMD3.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||FRMD3 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Putative tumor suppressor gene that may be implicated in the origin and progression of lung cancer.|
|Cellular Location||Membrane; Single-pass membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
Protein 4.1 of red blood cells, or 4.1R (EPB41; MIM 130500), is a multifunctional protein essential for maintaining erythrocyte shape and membrane mechanical properties. The protein 4.1 family comprises a group of structural proteins that includes, in addition to 4.1R, 4.1G (general type; MIM 603237), 4.1B (brain type; MIM 605331), 4.1N (neuron type; MIM 602879), and 4.1O (ovary type).
Maeda, S., et al. Diabetes (2010) In press :
Rose, J. Phd, et al. Mol. Med. (2010) In press :
Pezzolesi, M.G., et al. Diabetes 58(6):1403-1410(2009)
Haase, D., et al. Oncogene 26(30):4464-4468(2007)
Ni, X., et al. J. Hum. Genet. 48(2):101-106(2003)
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