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CDH11 Antibody (C-term)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AP18528b | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP18528b-ev20 | 20 ug 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
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- Backgrounds
CDH11 Antibody (C-term) - Product info | |
| Application | WB
|
| Primary Accession | P55287 |
| Other Accession | P55288, NP_001788 |
| Reactivity | Human, Mouse |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 87965 Da |
CDH11 Antibody (C-term) - Additional info | |
| Gene ID 1009 | |
| Other Names CDH11; Cadherin-11; OSF-4; Osteoblast cadherin | |
| Target/Specificity This CDH11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 621-650 amino acids from the C-terminal region of human CDH11. | |
| Dilution WB~~1:100~500WB~~1:1000 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions CDH11 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. | |
CDH11 Antibody (C-term) - Protein Information | |
| Name CDH11 | |
| Function Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types | |
| Cellular Location Cell membrane; Single-pass type I membrane protein | |
| Tissue Location Expressed mainly in brain but also found in other tissues. Expressed in neuroblasts | |
CDH11 Antibody (C-term) - Related products
AP18528b: CDH11 Antibody (C-term)
CDH11 Antibody (C-term) - Application data
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CDH11 Antibody (C-term) (Cat. #AP18528b) western blot analysis in mouse brain tissue lysates (35ug/lane).This demonstrates the CDH11 antibody detected the CDH11 protein (arrow).
CDH11 Antibody (C-term) - Research Areas
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BACKGROUND
This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance.
REFERENCES
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) : Sachdeva, M., et al. Cancer Res. 70(1):378-387(2010) Canova, C., et al. Cancer Res. 69(7):2956-2965(2009) Farina, A.K., et al. PLoS ONE 4 (3), E4797 (2009) : Brieger, J., et al. APMIS 116(12):1050-1057(2008)
