HEPHL1 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | Q6MZM0 |
Other Accession | NP_001092142.1 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 131603 Da |
Antigen Region | 199-225 aa |
Gene ID | 341208 |
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Other Names | Hephaestin-like protein 1, 1---, HEPHL1 |
Target/Specificity | This HEPHL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 199-225 amino acids from the N-terminal region of human HEPHL1. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | HEPHL1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | HEPHL1 |
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Function | Is a copper-binding glycoprotein with ferroxidase activity. It oxidizes Fe(2+) to Fe(3+) without releasing radical oxygen species (PubMed:31125343). May be involved in the regulation of intracellular iron content (PubMed:31125343). |
Cellular Location | Membrane; Single-pass type I membrane protein |
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Provided below are standard protocols that you may find useful for product applications.
Background
HEPHL1 may function as a ferroxidase and may be involved in copper transport and homeostasis (By similarity).
References
Rose, J. Phd, et al. Mol. Med. (2010) In press :
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