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HEPHL1 Antibody (N-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - HEPHL1 Antibody (N-term) AP18557a
    HEPHL1 Antibody (N-term) (Cat. #AP18557a) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the HEPHL1 antibody detected the HEPHL1 protein (arrow).
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q6MZM0
Other Accession NP_001092142.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 131603 Da
Antigen Region 199-225 aa
Additional Information
Gene ID 341208
Other Names Hephaestin-like protein 1, 1---, HEPHL1
Target/Specificity This HEPHL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 199-225 amino acids from the N-terminal region of human HEPHL1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsHEPHL1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name HEPHL1
Function Is a copper-binding glycoprotein with ferroxidase activity. It oxidizes Fe(2+) to Fe(3+) without releasing radical oxygen species (PubMed:31125343). May be involved in the regulation of intracellular iron content (PubMed:31125343).
Cellular Location Membrane; Single-pass type I membrane protein
Citations (0)
citation

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Background

HEPHL1 may function as a ferroxidase and may be involved in copper transport and homeostasis (By similarity).

References

Rose, J. Phd, et al. Mol. Med. (2010) In press :

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$ 365.00
$ 140.00
Cat# AP18557a
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