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>   home   >   Products   >   Primary Antibodies   >   HIST1H2BH/HIST1H2BK/HIST3H2BB Antibody (Center)   

HIST1H2BH/HIST1H2BK/HIST3H2BB Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - HIST1H2BH/HIST1H2BK/HIST3H2BB Antibody (Center) AP18559c
    HIST1H2BH/HIST1H2BK/HIST3H2BB Antibody (Center) (Cat. #AP18559c) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the HIST1H2BH/HIST1H2BK/HIST3H2BB antibody detected the HIST1H2BH/HIST1H2BK/HIST3H2BB protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q93079
Other Accession P57053, Q9PSW9, P0C1H5, P0C1H4, Q6PC60, Q8CGP0, Q8N257, Q9D2U9, Q5QNW6, Q64524, Q16778, Q64525, Q00715, Q5BJA5, P0C1H3, P62808, Q8CGP2, P23527, Q99877, Q32L48, P10854, Q99879, Q99880, Q8CGP1, O60814, Q2M2T1, P06899, Q64478, P10853, P58876, Q6ZWY9, P62807
Reactivity Human
Predicted Xenopus, Mouse, Bovine, Chicken, Zebrafish, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 13892 Da
Antigen Region 26-52 aa
Additional Information
Gene ID 8345
Other Names Histone H2B type 1-H, Histone H2Bj, H2B/j, HIST1H2BH, H2BFJ
Target/Specificity This HIST1H2BH/HIST1H2BK/HIST3H2BB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-52 amino acids from the Central region of human HIST1H2BH/HIST1H2BK/HIST3H2BB.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsHIST1H2BH/HIST1H2BK/HIST3H2BB Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms H2BFJ
Function Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Cellular Location Nucleus. Chromosome.
Citations (0)

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Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2B family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq].


Kim, S.C., et al. Mol. Cell 23(4):607-618(2006)
Beck, H.C., et al. Mol. Cell Proteomics 5(7):1314-1325(2006)
Pavri, R., et al. Cell 125(4):703-717(2006)
Bonenfant, D., et al. Mol. Cell Proteomics 5(3):541-552(2006)
Siuti, N., et al. J. Proteome Res. 5(2):233-239(2006)

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Cat# AP18559c
(40 western blots)
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