|Application ||WB, E|
|Other Accession||A1L1A6, NP_116121.2|
|Calculated MW||86240 Da|
|Antigen Region||103-131 aa|
|Other Names||Interleukin-17 receptor C, IL-17 receptor C, IL-17RC, Interleukin-17 receptor homolog, IL17Rhom, Interleukin-17 receptor-like protein, IL-17RL, ZcytoR14, IL17RC|
|Target/Specificity||This IL17RC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 103-131 amino acids from the N-terminal region of human IL17RC.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||IL17RC Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Cellular Location||Cell membrane; Single-pass type I membrane protein. Note=Soluble isoforms may be produced|
|Tissue Location||Expressed in brain, cartilage, colon, heart, intestine, kidney, liver, lung, muscle, placenta, and prostate Low expression in thymus and leukocytes. Expressed (at protein level) in prostate and prostate cancer, skeletal muscle, kidney and placenta.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a single-pass transmembrane protein that shares limited similarity with the interleukin-17 receptor. Multiple alternatively spliced transcript variants encoding different isoforms have been detected for this gene, but the full-length nature of only three have been determined to date.
Pickens, S.R., et al. J. Immunol. 184(6):3233-3241(2010)
Wright, J.F., et al. J. Immunol. 181(4):2799-2805(2008)
Zrioual, S., et al. J. Immunol. 180(1):655-663(2008)
Kuestner, R.E., et al. J. Immunol. 179(8):5462-5473(2007)
Haudenschild, D.R., et al. Prostate 66(12):1268-1274(2006)
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