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>   home   >   Products   >   Primary Antibodies   >   Immunology   >   IL17RC Antibody (N-term)   

IL17RC Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - IL17RC Antibody (N-term) AP18560a
    IL17RC Antibody (N-term) (Cat. #AP18560a) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the IL17RC antibody detected the IL17RC protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8NAC3
Other Accession A1L1A6, NP_116121.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 86240 Da
Antigen Region 103-131 aa
Additional Information
Gene ID 84818
Other Names Interleukin-17 receptor C, IL-17 receptor C, IL-17RC, Interleukin-17 receptor homolog, IL17Rhom, Interleukin-17 receptor-like protein, IL-17RL, ZcytoR14, IL17RC
Target/Specificity This IL17RC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 103-131 amino acids from the N-terminal region of human IL17RC.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsIL17RC Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name IL17RC
Function Receptor for IL17A and IL17F homodimers as part of a heterodimeric complex with IL17RA (PubMed:16785495). Receptor for the heterodimer formed by IL17A and IL17B as part of a heterodimeric complex with IL17RA (PubMed:18684971). Has also been shown to be the cognate receptor for IL17F and to bind IL17A with high affinity without the need for IL17RA (PubMed:17911633). Activation of IL17RC leads to induction of expression of inflammatory chemokines and cytokines such as CXCL1 (PubMed:16785495).
Cellular Location Cell membrane; Single-pass type I membrane protein. Note=Soluble isoforms may be produced
Tissue Location Expressed in prostate, skeletal muscle, kidney and placenta (at protein level) (PubMed:11706037). Expressed in brain, cartilage, colon, heart, intestine, kidney, liver, lung, muscle, placenta, and prostate (PubMed:11706037). Also detected in thyroid, trachea and adrenal gland (PubMed:17911633). Low expression in thymus and leukocytes (PubMed:11706037)
Research Areas
Citations (0)

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This gene encodes a single-pass transmembrane protein that shares limited similarity with the interleukin-17 receptor. Multiple alternatively spliced transcript variants encoding different isoforms have been detected for this gene, but the full-length nature of only three have been determined to date.


Pickens, S.R., et al. J. Immunol. 184(6):3233-3241(2010)
Wright, J.F., et al. J. Immunol. 181(4):2799-2805(2008)
Zrioual, S., et al. J. Immunol. 180(1):655-663(2008)
Kuestner, R.E., et al. J. Immunol. 179(8):5462-5473(2007)
Haudenschild, D.R., et al. Prostate 66(12):1268-1274(2006)

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$ 295.00
$ 99.00
Cat# AP18560a
(40 western blots)
Availability: In Stock
Bulk Size
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