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HIRIP3 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - HIRIP3 Antibody (Center) AP18580c
    HIRIP3 Antibody (Center) (Cat. #AP18580c) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the HIRIP3 antibody detected the HIRIP3 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9BW71
Other Accession NP_003600.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 61957 Da
Antigen Region 287-316 aa
Additional Information
Gene ID 8479
Other Names HIRA-interacting protein 3, HIRIP3
Target/Specificity This HIRIP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 287-316 amino acids from the Central region of human HIRIP3.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsHIRIP3 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function May play a role in chromatin function and histone metabolism via its interaction with HIRA and histones.
Cellular Location Nucleus. Note=Nuclear throughout the cell cycle and is excluded from condensed chromatin during mitosis
Tissue Location Widely expressed. Isoform 1 is predominant in skeletal muscle. Isoform 2 is predominant in liver and heart
Research Areas
Citations (0)

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The HIRA protein shares sequence similarity with Hir1p and Hir2p, the two corepressors of histone gene transcription characterized in the yeast, Saccharomyces cerevisiae. The structural features of the HIRA protein suggest that it may function as part of a multiprotein complex. Recently, several cDNAs encoding HIRA-interacting proteins, or HIRIPs, have been identified. In vitro, the HIRIP3 gene product binds HIRA, as well as H2B and H3 core histones, indicating that a complex containing HIRA-HIRIP3 could function in some aspects of chromatin and histone metabolism.


Kumar, R.A., et al. PLoS ONE 4 (2), E4582 (2009) :
Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)
Assrir, N., et al. Biol. Chem. 388(4):391-398(2007)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Olsen, J.V., et al. Cell 127(3):635-648(2006)

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$ 295.00
$ 99.00
Cat# AP18580c
(40 western blots)
Availability: In Stock
Bulk Size
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